81569-28-0 Usage
Uses
Used in Pharmaceutical Industry:
Methyl 2-bromo-5-isopropyl-1,3-thiazole-4-carboxylate is used as a synthetic intermediate for the development of various pharmaceuticals. Its unique structure and reactivity make it a valuable component in the synthesis of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, Methyl 2-bromo-5-isopropyl-1,3-thiazole-4-carboxylate serves as a key intermediate in the production of pesticides. Its incorporation into the formulation of these chemicals aids in the development of more effective and targeted pest control solutions, enhancing agricultural productivity and crop protection.
Used in Organic Synthesis:
Methyl 2-bromo-5-isopropyl-1,3-thiazole-4-carboxylate is utilized as a versatile building block in organic synthesis. Its reactivity allows for the preparation of diverse heterocyclic compounds, which are essential in the creation of complex organic molecules with various applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 81569-28-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,5,6 and 9 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 81569-28:
(7*8)+(6*1)+(5*5)+(4*6)+(3*9)+(2*2)+(1*8)=150
150 % 10 = 0
So 81569-28-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H10BrNO2S/c1-4(2)6-5(7(11)12-3)10-8(9)13-6/h4H,1-3H3
81569-28-0Relevant academic research and scientific papers
IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION
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Paragraph 00192, (2013/11/18)
The present invention provides thiazole compounds of Formula I wherein W, Y, R0, R2, R4, R5, R6, R7, X1, X2, X3 and X4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.
The Preparation of Thiazole-4- and -5-carboxylates, and an Infrared Study of their Rotational Isomers
Barton, Anne,Breukelman, Stephen P.,Kaye, Perry T.,Meakins, G. Denis,Morgan, David J.
, p. 159 - 164 (2007/10/02)
Convenient general procedures have been developed for preparing series of thiazole-4- and -5-carboxylates containing alkyl and halogeno substituents.While both series of esters show i.r. carbonyl doublets caused by rotational isomerism, the more intense absorptions of the 4-carboxylates are the lower wavenumber components, whereas those of the 5-carboxylates are the higher wavenumber components.In both series the stronger bands arise from the thermochemically more stable forms; identification of these forms as the carbonyl O,S-syn-s-trans rotamers is more certain with the 4-carboxylates than with the 5-carboxylates.
