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81576-60-5

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81576-60-5 Usage

Type

Deuterated form of 1-bromodecane

Primary Uses

a. Solvent in organic synthesis
b. Reagent in organic synthesis
c. Production of pharmaceuticals and agrochemicals

Deuterium Content

Contains deuterium atoms instead of hydrogen atoms

Applications in NMR Spectroscopy

a. Standard for calibration in NMR experiments
b. Tracer for studying behavior of organic compounds in chemical and biological processes

Hazardous Nature

Considered a hazardous chemical and should be handled with caution

Check Digit Verification of cas no

The CAS Registry Mumber 81576-60-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,5,7 and 6 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 81576-60:
(7*8)+(6*1)+(5*5)+(4*7)+(3*6)+(2*6)+(1*0)=145
145 % 10 = 5
So 81576-60-5 is a valid CAS Registry Number.

81576-60-5Downstream Products

81576-60-5Relevant academic research and scientific papers

The structural and dynamic properties of 1-bromodecane in urea inclusion compounds investigated by solid-state 1H, 13C and 2H NMR spectroscopy

Yang, Xiaorong,Mueller, Klaus

experimental part, p. 514 - 522 (2011/10/18)

For asymmetric guest molecules in urea, the end-groups of two adjacent guest molecules may arrange in three different ways: head-head, head-tail and tail-tail. Solid-state 1H and 13C NMR spectroscopy is used to study the structural properties of 1-bromodecane in urea. It is found that the end groups of the guest molecules are randomly arranged. The dynamic characteristics of 1-bromodecane in urea inclusion compounds are probed by variable-temperature solid-state 2H NMR spectroscopy (line shapes, spin-spin relaxation: T2, spin-lattice relaxation: T1Z and T1Q) between 120 K and room temperature. The comparison between the simulation and experimental data shows that the dynamic properties of the guest molecules can be described in a quantitative way using a non-degenerate three-site jump process in the low-temperature phase and a degenerate three-site jump in the high-temperature phase, in combination with the small-angle wobbling motion. The kinetic parameters can be derived from the simulation. Copyright

Loss of benzene to generate an enolate anion by a site-specific double-hydrogen transfer during CID fragmentation of o-alkyl ethers of ortho-hydroxybenzoic acids

Attygalle, Athula B.,Bialecki, Jason B.,Nishshanka, Upul,Weisbecker, Carl S.,Ruzicka, Josef

experimental part, p. 1224 - 1234 (2009/09/29)

Collision-induced dissociation of anions derived from orffco- alkyloxybenzoic acids provides a facile way of producing gaseous enolate anions. The alkyloxyphenyl anion produced after an initial loss of CO2 undergoes elimination of a benzene molecule by a double-hydrogen transfer mechanism, unique to the ortho isomer, to form an enolate anion. Deuterium labeling studies confirmed that the two hydrogen atoms transferred in the benzene loss originate from positions 1 and 2 of the alkyl chain. An initial transfer of a hydrogen atom from the C-l position forms a phenyl anion and a carbonyl compound, both of which remain closely associated as an ion/neutral complex. The complex breaks either directly to give the phenyl anion by eliminating the neutral carbonyl compound, or to form an enolate anion by transferring a hydrogen atom from the C-2 position and eliminating a benzene molecule in the process. The pronounced primary kinetic isotope effect observed when a deuterium atom is transferred from the C-l position, compared to the weak effect seen for the transfer from the C-2 position, indicates that the first transfer is the rate determining step. Quantum mechanical calculations showed that the neutral loss of benzene is a thermodynamically favorable process. Under the conditions used, only the spectra from ortho isomers showed peaks at mlz 77 for the phenyl anion and mlz 93 for the phenoxyl anion, in addition to that for the ortho-specific enolate anion. Under high collision energy, the ortho isomers also produce a peak at mlz 137 for an alkene loss. The spectra of meta and para compounds show a peak at mlz 92 for the distonic anion produced by the homolysis of the O-C bond. Moreover, a small peak at mlz 136 for a distonic anion originating from an alkyl radical loss allows the differentiation of para compounds from meta isomers. Copyright

The Cleavage of a CC Double Bond after Chemical Ionization with NO+-A Complex Rearrangement Process

Bukovits, G. J.,Budzikiewicz, H.

, p. 23 - 26 (2007/10/02)

The fragmentation of alkenes after chemical ionization with NO+, involving cleavage of the double bond, has been elucidated by deuterium labelling.

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