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1-Fluoro-3-(2,2,2-trifluoroethyl)benzene is an organic compound with the chemical formula C8H6F4. It is a colorless liquid at room temperature and is characterized by the presence of a benzene ring with a fluorine atom at the 1-position and a trifluoroethyl group at the 3-position. 1-FLUORO-3-(2,2,2-TRIFLUOROETHYL)BENZENE is primarily used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its fluorinated nature, it offers unique properties such as increased lipophilicity and metabolic stability, which can be beneficial in the development of new drugs and chemical compounds. However, it is important to handle this substance with care, as it may have potential health and environmental risks.

81577-08-4

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81577-08-4 Usage

Molecular Structure

Benzene derivative with a fluorine atom attached to the first carbon of the benzene ring and a trifluoroethyl group attached to the third carbon.

Type of Compound

Highly fluorinated compound

Applications

Used in organic synthesis and as a building block for the creation of more complex fluorinated compounds.

Physical Properties

Unique chemical and physical properties due to its highly fluorinated nature.

Precautions

Handle with caution as its fluorinated nature may pose risks to human health and the environment.

Hazardous Nature

Potential risks to human health and the environment due to its fluorinated nature.

Safety Measures

Proper handling, storage, and disposal procedures should be followed to minimize risks.

Check Digit Verification of cas no

The CAS Registry Mumber 81577-08-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,5,7 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 81577-08:
(7*8)+(6*1)+(5*5)+(4*7)+(3*7)+(2*0)+(1*8)=144
144 % 10 = 4
So 81577-08-4 is a valid CAS Registry Number.

81577-08-4Relevant academic research and scientific papers

MECHANISMS OF FREE-RADICAL REACTIONS. XIII. MECHANISM AND SELECTIVITY OF THE FREE-RADICAL HALOGENATION OF ALKYL AROMATIC HYDROCARBONS WITH FLUOROALKYL SUBSTITUENTS

Dneprovskii, A. S.,Eliseenkov, E. V.,Mil'tsov, S. A.

, p. 317 - 324 (2007/10/02)

The free-radical chlorination and bromination of 1-fluoro-2-arylethanes and 1,1,1-trifluoro-2-arylethanes was studied by the method of competing reactions.In all cases a good correalation between log krel and the Brown ?+ constants was observed.The variation of the selectivity in the transition from one reaction series to the other indicates that two independent factors which determine the reactivity (the change in the dissociation energy of the C-H bond and the polar effect of the substituents) have a simultaneous effect.

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