81577-13-1

Basic information

• Product Name: 1-(1-Chloro-2,2,2-trifluoro-ethyl)-4-fluoro-benzene
• Synonyms: 1-(1-Chloro-2,2,2-trifluoro-ethyl)-4-fluoro-benzene
• CAS NO: 81577-13-1
• Molecular Weight: 212.574
• Mol File: 81577-13-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(1-Chloro-2,2,2-trifluoro-ethyl)-4-fluoro-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1-Chloro-2,2,2-trifluoro-ethyl)-4-fluoro-benzene(81577-13-1)
• EPA Substance Registry System: 1-(1-Chloro-2,2,2-trifluoro-ethyl)-4-fluoro-benzene(81577-13-1)

Safety Data

• Hazardous Substances Data: 81577-13-1(Hazardous Substances Data)

Upstream product

• 17556-41-1 2,2,2-trifluoro-1-(4-fluorophenyl)ethanol 
• 50561-99-4 1-fluoro-4-(2,2,2-trifluoroethyl)benzene 
• 384-65-6 1-chloro-2,2,2-trifluoroethylbenzene 
• 128408-32-2 C₈H₅F₄⁽¹⁺⁾ 

Downstream Products

• 128408-32-2 C₈H₅F₄⁽¹⁺⁾ 
• 939-99-1 4-trifluoromethylbenzyl chloride 
• 456-42-8 m-fluorobenzyl chloride 
• 50561-99-4 1-fluoro-4-(2,2,2-trifluoroethyl)benzene 

Relevant articles and documents

Stille cross-coupling of secondary and tertiary α-(trifluoromethyl)-benzyl chlorides with allylstannanes

A Stille cross-coupling reaction was developed that delivers for the first time trifluoromethyl-substituted homoallyl compounds from α-(trifluoromethyl)benzyl chlorides and allylstannanes. This reaction proceeds even with low catalyst loadings (1 mol%) vi

MECHANISMS OF FREE-RADICAL REACTIONS. XIII. MECHANISM AND SELECTIVITY OF THE FREE-RADICAL HALOGENATION OF ALKYL AROMATIC HYDROCARBONS WITH FLUOROALKYL SUBSTITUENTS

The free-radical chlorination and bromination of 1-fluoro-2-arylethanes and 1,1,1-trifluoro-2-arylethanes was studied by the method of competing reactions.In all cases a good correalation between log krel and the Brown ?+ constants was observed.The variation of the selectivity in the transition from one reaction series to the other indicates that two independent factors which determine the reactivity (the change in the dissociation energy of the C-H bond and the polar effect of the substituents) have a simultaneous effect.