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Usage

Uses

Used in Pharmaceutical Industry:
1-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-2-chloroethanone is used as an intermediate in the synthesis of anthocyanins, which are a class of natural pigments responsible for the vibrant colors in fruits, vegetables, and other plant-based products. These anthocyanins have been recognized for their potential health benefits, including antioxidant, anti-inflammatory, and anti-cancer properties.
Used in Cosmetic Industry:
In the cosmetic industry, 1-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-2-chloroethanone is used as a precursor in the production of anthocyanin-based colorants. These colorants are valued for their natural origin, safety, and ability to provide a wide range of hues, making them ideal for use in various cosmetic products such as lipsticks, eyeshadows, and blushes.
Used in Food Industry:
1-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-2-chloroethanone is also utilized in the food industry for the preparation of anthocyanin-based food colorants. These colorants offer a natural alternative to synthetic dyes, providing a healthier and more appealing option for consumers. They can be used in a variety of food products, including beverages, confectionery, and baked goods.
Used in Nutraceutical Industry:
In the nutraceutical sector, 1-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-2-chloroethanone plays a role in the development of anthocyanin-rich supplements and functional foods. These products are designed to deliver the health-promoting benefits of anthocyanins, such as their antioxidant and anti-inflammatory effects, to consumers seeking natural ways to improve their overall health and well-being.

Upstream product

• 2051-90-3 Dichlorodiphenylmethane 
• 99-40-1 2-chloro-3',4'-dihydroxyacetophenone 

Downstream Products

• 185448-77-5 3-{Benzyl-[2-(2,2-diphenyl-benzo[1,3]dioxol-5-yl)-2-oxo-ethyl]-amino}-propionic acid methyl ester 
• 185448-76-4 3-{Benzyl-[2-(2,2-diphenyl-benzo[1,3]dioxol-5-yl)-2-oxo-ethyl]-amino}-propionic acid ethyl ester 
• 917379-97-6 2-iodo-3',4'-diphenylmethylenedioxyacetophenone 
• 185448-82-2 3-{Benzyl-[2-(2,2-diphenyl-benzo[1,3]dioxol-5-yl)-2-hydroxy-ethyl]-amino}-propionic acid ethyl ester 
• 185448-84-4 3-{Benzyl-[2-(2,2-diphenyl-benzo[1,3]dioxol-5-yl)-2-hydroxy-ethyl]-amino}-propionic acid methyl ester 
• 185448-92-4 3-[2-(3,4-Dihydroxy-phenyl)-2-hydroxy-ethylamino]-propionic acid ethyl ester 

Relevant academic research and scientific papers

METHOD FOR THE SYNTHESIS OF ANTHOCYANINS

The present invention relates to methods of preparing anthocyanins, and methods of preparing precursors of anthocyanins. The methods utilise a coupling reaction between a sugar and a suitable electrophilic precursor to form Eastern half intermediates, that are then reacted with Western half intermediates to form the target anthocyanins. Some Eastern half intermediates and electrophilic precursors also form part of the invention.

Soft β-adrenergic agonists for the topical treatment of psoriasis

The soft-drug 1 (R = Me, Et) and pro-soft-drug 3 have been prepared as models of topical anti-psoriatic β-adrenergic agonists. The chemical hydrolysis of 3 proceeded via the acid 18 with a maximum stability at apparent pH ~4.0. In the presence of PLCE, the required metabolism of 3 to the soft-drug 1 (R = Et) was achieved, which slowly degraded to the dihydroxy acid 2. Soft-drug 1 (R = Et) was poorly transported across a silicone membrane, whereas the pro-soft-drug 3 was more efficient and the rate increased over the donor apparent pH range 3-8. Soft-drug 1 (R = Et) was a full β-agonist on the guinea-pig tracheal preparation, whereas the pro-soft-drug 3 produced only slowly developing responses at high concentrations (> 10 μM).