816438-46-7

Basic information

• Product Name: 3-(4-Chlorobutyl)indoline-5-carbonitrile
• Synonyms: 3-(4-Chlorobutyl)indoline-5-carbonitrile;3-(4-Chlorobutyl)-2,3-dihydro-1H-Indole-5-carbonitrile;Vilazodone Impurity B
• CAS NO: 816438-46-7
• Molecular Formula: C13H15ClN2
• Molecular Weight: 234.7246
• Product Categories: Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 816438-46-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 364.5±42.0 °C(Predicted)
• Appearance: /
• Density: 1.17±0.1 g/cm3(Predicted)
• PKA: 1.74±0.40(Predicted)
• CAS DataBase Reference: 3-(4-Chlorobutyl)indoline-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4-Chlorobutyl)indoline-5-carbonitrile(816438-46-7)
• EPA Substance Registry System: 3-(4-Chlorobutyl)indoline-5-carbonitrile(816438-46-7)

Safety Data

• Hazardous Substances Data: 816438-46-7(Hazardous Substances Data)

Usage

Uses

3-(4-Chlorobutyl)indoline-5-carbonitrile is a reactant that has been used in the preparation of the antidepressant drug Vilazodone (V265000)

Upstream product

• 276863-95-7 3-(4-chlorobutanoyl)-1H-indole-5-carbonitrile 

Downstream Products

• 1398359-30-2 C₂₀H₂₁ClN₂O₂S 

Relevant articles and documents

INDOLE DERIVATIVES AS SEROTONIN REUPTAKE INHIBITORS

Disclosed are compounds of formula (I), the use thereof for producing a medicament utilized for treating diseases related to the serotonin receptor and/or serotonin reuptake, especially for producing a medicament utilized as an anxiolytic, antidepressant, neuroleptic, and/or antihypertensive and/or for positively influencing obsessive-compulsive behavior (OCD), sleeping disorders, tardive dyskinesia, learning disorders, age-related memory defects, eating disorders such as bulimia, and/or sexual dysfunctions. The inventive compounds bond to the 5-HT1A receptor.