816454-03-2Relevant academic research and scientific papers
Highly efficient synthesis of (R)- and (S)-piperazic acids using proline-catalyzed asymmetric α-hydrazination
Henmi, Yoshiaki,Makino, Kazuishi,Yoshitomi, Yayoi,Hara, Osamu,Hamada, Yasumasa
, p. 3477 - 3481 (2007/10/03)
The highly efficient synthesis of (R)- and (S)-piperazic acids, components of naturally occurring antibiotic cyclodepsipeptides, was achieved in 80% overall yield by the use of a proline-catalyzed asymmetric α-hydrazination as the key step.
