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2-Pyrazinecarboxylicacid, 1,6-dihydro-3-methyl-5-(1-methylethyl)-6-oxo-, ethyl ester
Cas No: 816458-60-3
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Henan Tianfu Chemical Co., Ltd.
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2-PYRAZINECARBOXYLIC ACID 1,6-DIHYDRO-3-METHYL-5-(ISOPROPYL)-6-OXO-,ETHYL ESTER
Cas No: 816458-60-3
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Hangzhou Fandachem Co.,Ltd
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2-Pyrazinecarboxylicacid,1,6-dihydro-3-methyl-5-(1-methylethyl)-6-oxo-,ethylester(9CI)
Cas No: 816458-60-3
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ZHEJIANG JIUZHOU CHEM CO.,LTD
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816458-60-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 816458-60-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,1,6,4,5 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 816458-60:
(8*8)+(7*1)+(6*6)+(5*4)+(4*5)+(3*8)+(2*6)+(1*0)=183
183 % 10 = 3
So 816458-60-3 is a valid CAS Registry Number.

816458-60-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	2-Pyrazinecarboxylicacid,1,6-dihydro-3-methyl-5-(1-methylethyl)-6-oxo-,ethylester(9CI)

1.2 Other means of identification

Product number	-
Other names	5-isopropyl-3,7-dimethyl-1H-inden-1-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:816458-60-3 SDS

816458-60-3Upstream product

816458-60-3Downstream Products

816458-60-3Relevant articles and documents

Design and optimization of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1 ((DGAT1) leading to a clinical candidate dimethylpyrazinecarboxamide phenylcyclohexylacetic acid (AZD7687)

Barlind, Jonas G.,Bauer, Udo A.,Birch, Alan M.,Birtles, Susan,Buckett, Linda K.,Butlin, Roger J.,Davies, Robert D.M.,Eriksson, Jan W.,Hammond, Clare D.,Hovland, Ragnar,Johannesson, Petra,Johansson, Magnus J.,Kemmitt, Paul D.,Lindmark, Bo T.,Morentin Gutierrez, Pablo,Noeske, Tobias A.,Nordin, Andreas,O'Donnell, Charles J.,Petersson, Annika U.,Redzic, Alma,Turnbull, Andrew V.,Vinblad, Johanna

, p. 10610 - 10629 (2013/02/23)

A new series of pyrazinecarboxamide DGAT1 inhibitors was designed to address the need for a candidate drug with good potency, selectivity, and physical and DMPK properties combined with a low predicted dose in man. Rational design and optimization of this series led to the discovery of compound 30 (AZD7687), which met the project objectives for potency, selectivity, in particular over ACAT1, solubility, and preclinical PK profiles. This compound showed the anticipated excellent pharmacokinetic properties in human volunteers.

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CAS

816458-60-3