81658-88-0

Upstream product

• 77771-02-9 3-bromo-4-fluorobenzaldehyde 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 1357614-78-8 tert-butyl 3-(2-bromo-4-(dimethoxymethyl)phenyl)-3-cyanoazetidine-1-carboxylate 
• 1357614-77-7 3-(2-bromo-4-(dimethoxymethyl)phenyl)azetidine-3-carbonitrile 
• 1357614-79-9 tert-butyl 3-(2-bromo-4-((hydroxyimino)methyl)phenyl)-3-cyanoazetidine-1-carboxylate 
• 1357614-80-2 tert-butyl 3-(2-bromo-4-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)phenyl)-3-cyanoazetidine-1-carboxylate 
• 1357614-82-4 3-(2-bromo-4-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)phenyl)azetidine-3-carbonitrile 
• 1357610-36-6 3-(2-bromo-4-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)phenyl)-1-(cyclopropanecarbonyl)azetidine-3-carbonitrile 
• 1357610-39-9 1-(cyclopropanecarbonyl)-3-(4-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)phenyl)azetidine-3-carbonitrile 
• 1357614-76-6 1-benzhydryl-3-(2-bromo-4-(diethoxymethyl)phenyl)azetidine-3-carbonitrile 
• 1398608-97-3 5'-(5-(3,5-bis(trifluoromethyl)phenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-1-(2-(methylsulfonyl)acetyl)spiro[azetidine-3,1'-isoindolin]-3'-one 
• 1398609-78-3 tert-butyl 5'-(5-(3,5-bis(trifluoromethyl)phenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'-oxospiro[azetidine-3,1'-isoindoline]-1-carboxylate 
• 1398609-75-0 C₂₈H₂₉BrN₂O₃ 
• 1398609-74-9 1-benzhydryl-5'-(diethoxymethyl)spiro[azetidine-3,1'-isoindolin]-3'-one 
• 1398609-73-8 1-benzhydryl-3-(2-bromo-4-(diethoxymethyl)phenyl)azetidine-3-carboxylic acid 

Relevant academic research and scientific papers

SPIROCYCLIC ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS

The invention recites spirocyclic isoxazoline derivatives of Formula (V.1), Formula (V.2), Formula (V.1.1), and Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, processes for making, and their use as a parasi

ISOXAZOLINE DERIVATIVES AS ANTIPARASITIC AGENTS

This invention recites isoxazoline substituted azetidine derivatives of Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, and their use as a parasiticide in mammals and birds. R1a, R1b, R1c, R2, R3, R4, R6, and n are as described herein.