81659-47-4

Basic information

• Product Name: ((4S,5S)-5-Phenyl-2-pyridin-3-yl-4,5-dihydro-oxazol-4-yl)-methanol
• Synonyms: ((4S,5S)-5-Phenyl-2-pyridin-3-yl-4,5-dihydro-oxazol-4-yl)-methanol
• CAS NO: 81659-47-4
• Molecular Weight: 254.288
• Mol File: 81659-47-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ((4S,5S)-5-Phenyl-2-pyridin-3-yl-4,5-dihydro-oxazol-4-yl)-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: ((4S,5S)-5-Phenyl-2-pyridin-3-yl-4,5-dihydro-oxazol-4-yl)-methanol(81659-47-4)
• EPA Substance Registry System: ((4S,5S)-5-Phenyl-2-pyridin-3-yl-4,5-dihydro-oxazol-4-yl)-methanol(81659-47-4)

Safety Data

• Hazardous Substances Data: 81659-47-4(Hazardous Substances Data)

Upstream product

• 28143-91-1 (1S,2S)-2-amino-1-phenyl-1,3-diol 
• 56624-12-5 ethyl (3-pyridyl)imidate dihydrochloride 

Downstream Products

• 81659-53-2 4-Butyl-3-((4S,5S)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-4H-pyridine-1-carboxylic acid tert-butyl ester 
• 81659-56-5 3-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-4-phenyl-pyridine 
• 81659-49-6 4-Butyl-3-((4S,5S)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-1,4-dihydro-pyridine 
• 81659-50-9 2-Butyl-5-((4S,5S)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-1,2-dihydro-pyridine 
• 98704-91-7 2-[5-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-ylmethoxy]-1-(1,4,7,10-tetraoxa-13-aza-cyclopentadec-13-yl)-ethanone 
• 98704-77-9 Acetic acid 5-((4S,5S)-4-methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-ylmethyl ester 
• 98704-76-8 5-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-2-methyl-pyridine 1-oxide 
• 98704-78-0 [5-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-pyridin-2-yl]-methanol 
• 98704-75-7 5-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-2-methyl-pyridine 
• 81659-55-4 3-((4S,5S)-4-Methoxymethyl-5-phenyl-4,5-dihydro-oxazol-2-yl)-4-methyl-pyridine 
• 81659-48-5 2-(3-pyridyl)-4(S)-(methoxymethyl)-5(S)-phenyl-Δ²-oxazoline 
• 81659-61-2 [(4S,5S)-5-Phenyl-2-(6-phenyl-pyridin-3-yl)-4,5-dihydro-oxazol-4-yl]-methanol 
• 81659-62-3 [(4S,5S)-5-Phenyl-2-(4-phenyl-pyridin-3-yl)-4,5-dihydro-oxazol-4-yl]-methanol 

Relevant articles and documents

Nicotinic Acid Lariat Ethers: Syntheses, Complexation, and Reduction

Combination of 2-(hydroxymethyl)-5-oxazolinylpyridine 16a with lariat ethers 21 and 23 generated chiral 6-methylnicotinic oxazoline lariat ethers 22 and 24, respectively.Chiral lariat ether 24b by stereoselective metal-directed addition of methylmagnesium bromide was converted to the corresponding enantiomerically enriched N-magnesio-1,4-dihydropyridine 26.Lariat 26 and the nonlariat analogue 31 both reduced α,α,α-trifluoroacetophenone in a NADH model-like reduction to give the S alcohol 32 in low enantiomeric excess.