81667-61-0Relevant articles and documents
Compounds with Bridgehead Nitrogen. Part 41. The Reaction between trans-2-Aminocycloalkanols and Formaldehyde
Barkworth, Peter M. R.,Crabb, Trevor A.
, p. 91 - 94 (2007/10/02)
trans-2-Aminocyclopentanol and trans-2-aminocyclohexanol condense with formaldehyde to give single isomers of NN'-methanoperhydrocycloalkanodioxadiazecines whereas trans-2-aminocycloheptanol and trans-2-aminocyclo-octanol give 1:1 mixtures of two isomeric bis(perhydrocycloalkano-oxazol-3-yl)methanes.The formation of the two types of dimer is explained in terms of differences in ring fusion strain.