81668-19-1

Upstream product

• 21916-51-8 1-methyl-4,6-diphenylpyridin-2(1H)-one 
• 64202-50-2 1,3-diethyl-2-oxo-4,6-diphenyl-1,2,3,4-tetrahydropyridine-3-carbonitrile 
• 17372-52-0 4,6-diphenyl-2H-pyran-2-one 
• 811-49-4 ethyllithium 
• 81668-35-1 1-ethyl-4,6-diphenyl-2-pyridone 

Relevant academic research and scientific papers

Simultaneous C-and N-alkylation of 2-oxo-4,6-diaryl-1,2,3,4- tetrahydropyridine-3-carbonitrile under solid-liquid phase-transfer conditions

The alkylation of 2-oxo-4,6-diaryl-1,2,3,4-tetrahydropyridine-3- carbonitrile 1 has been carried out using different alkyl/arylating agents in solid-liquid phase-transfer catalysis conditions. The aim was to study the effect of steric hindrance offered by

Heterocycle Stabilized Carbanions. Two Series of Anomalous Products from 1-Alkyl-4,6-diphenyl-2-pyridones

1-Methyl-, 1-ethyl, and 1-n-butyl-4,6-diphenyl-2-pyridones with lithium di-isopropylamide yield normal products with ketone and aldehydes as electrophiles, but dimeric derivatives with acid chlorides, esters, and alkyl halides.The alkylpyridones react with ethyl- and n-butyl-lithium and an electrophile to give products resulting from alkylation at the 3- and reaction with electrophile at the 4-position.Structures are supported by spectra and reaction mechanisms discussed.