81684-01-7

Upstream product

• 81684-00-6 [2-Oxo-4-((E)-2-oxo-4-phenyl-but-3-enyl)-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid 4-nitro-benzyl ester 
• 81902-83-2 [2-((Z)-4-Ethoxy-2-oxo-pent-3-enyl)-4-oxo-azetidin-1-yl]-(triphenyl-λ⁵-phosphanylidene)-acetic acid 4-nitro-benzyl ester 
• 81902-78-5 2-((Z)-3-Ethoxy-but-2-enoyl)-2-(4-oxo-azetidin-2-yl)-malonic acid dibenzyl ester 
• 81902-79-6 (Z)-5-Ethoxy-3-oxo-2-(4-oxo-azetidin-2-yl)-hex-4-enoic acid benzyl ester 
• 81683-98-9 4-((E)-2-Oxo-4-phenyl-but-3-enyl)-azetidin-2-one 
• 81902-80-9 4-((Z)-4-Ethoxy-2-oxo-pent-3-enyl)-azetidin-2-one 
• 83344-36-9 3-Chloro-4,8-dioxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 2365-48-2 Methyl thioglycolate 

Downstream Products

• 83344-28-9 4-Hydroxy-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-36-9 3-Chloro-4,8-dioxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-47-2 4-Acetoxy-3-(2-acetylamino-ethanesulfonyl)-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-46-1 4-Acetoxy-3-(2-acetylamino-ethanesulfinyl)-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-34-7 4-Acetoxy-3-(2-methoxy-ethanesulfinyl)-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-35-8 4-Acetoxy-3-(2-methoxy-ethanesulfonyl)-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-45-0 4-Acetoxy-3-(2-acetylamino-ethylsulfanyl)-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-51-8 3-(2-Methoxy-ethylsulfanyl)-4-methylcarbamoyloxy-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-49-4 4-Acetoxy-3-methoxycarbonylmethylsulfanyl-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-32-5 4-Acetoxy-8-oxo-3-phenylsulfanyl-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-33-6 4-Acetoxy-3-(2-methoxy-ethylsulfanyl)-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-31-4 (2R,3R,4S)-4-Acetoxy-8-oxo-3-phenylsulfanyl-1-aza-bicyclo[4.2.0]octane-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-43-8 3-(2-Acetylamino-ethylsulfanyl)-4-hydroxy-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 83344-37-0 3-(2-Acetylamino-ethylsulfanyl)-4,8-dioxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

STUDIES ON 1-CARBADETHIACEPHEMS, PART III: SYNTHESIS OF 2,3-DIFUNCTIONALISED 1-CARBADETHIACEPHEM DERIVATIVES

A novel C(3) chlorination of p-nitrobenzyl 1-carbadethia-2-oxocephem 4-carboxylate 1 with sulphur dichloride is described.Reaction of the resulting 3-chloro-compound 8 with various thiols, and modifications at C(2) provided the title compounds.