81709-99-1

Basic information

• Product Name: 3-methyl-3-aza-1,1-dicyano-2-phenyl-1-penten-5-ol
• CAS NO: 81709-99-1
• Molecular Weight: 227.266
• Mol File: 81709-99-1.mol

Chemical Properties

• CAS DataBase Reference: 3-methyl-3-aza-1,1-dicyano-2-phenyl-1-penten-5-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-3-aza-1,1-dicyano-2-phenyl-1-penten-5-ol(81709-99-1)
• EPA Substance Registry System: 3-methyl-3-aza-1,1-dicyano-2-phenyl-1-penten-5-ol(81709-99-1)

Safety Data

• Hazardous Substances Data: 81709-99-1(Hazardous Substances Data)

Upstream product

• 20334-42-3 sodium dicyanomethanide 
• 81592-54-3 N-methyl-2-phenyl-1,3-oxazolinium triflate 

Relevant articles and documents

REACTION PATHS OF 1,3-OXAZOLINIUM SALTS WITH STABILIZED CARBANIONS

Reaction of stabilized carbanions with 3-methyl-2-phenyl-1,3-oxazolinium triflate occurs both C5 and C2 sites with a regioselectivity depending partially on steric effects.The reaction at C2 site can result in the formation of 1,4-oxazepin derivatives.

A NEW ALKYLAMIDATION REACTION. REGIOSPECIFIC CONDENSATION OF CARBANIONS ON CYCLO 1,3-OXOIMMINIUM SALTS

Cyclo 1,3-oxoimminium salts are found to react regiospecifically with functional carbanions.Steric effects induced at the C-2 site on salts or at the carbanionic centers promote the condensation at the C-5 or C-6 opposite sites.A bulky substituent such as 2-mesityl group is a powerful auxiliary which not only modifies the steric environment at the reactive C-2 site but also contributes to enhance the reactivity of the cyclo oxoimminium ring.