817160-49-9Relevant academic research and scientific papers
Scandium-bipyridine-catalyzed, enantioselective alcoholysis of meso-epoxides
Tschoep, Andreas,Marx, Andreas,Sreekanth, Anakallil R.,Schneider, Christoph
, p. 2318 - 2327 (2007)
The scandium-bipyridine-catalyzed ring-opening of meso-epoxides with aliphatic alcohols has been studied. Aromatic epoxides were ring-opened with >90 % ee furnishing valuable 1,2-diol monoethers in typically good yields whereas aliphatic epoxides gave ris
Scandium-bipyridine-catalyzed enantioselective addition of alcohols and amines to meso-epoxides
Schneider, Christoph,Sreekanth, Anakallil R.,Mai, Enzo
, p. 5691 - 5694 (2007/10/03)
A winning combination of metal and ligand: The catalyst formed in situ from Sc(OTf)3 and bipyridine 1 (10 mol%) mediates the alcoholysis and aminolysis of Mieso-epoxides in high enantioselectivities and furnishes valuable chiral 1,2-diol monoethers 2 and 1,2-amino alcohols 3 as products (PMB = para-methoxybenzyl).
