817170-66-4

Usage

Uses

Used in Materials Science:
3',6'-BIS(4,4,5,5-TETRAMETHYL-1,3,2-DIOXOBOROLAN-2-YL)-SPIRO[ISOBENZOFURAN-1(3H),9'-[9H]XANTHEN]-3-ONE is used as a novel compound for the development of advanced materials due to its distinctive structural features and potential for integration into new material systems.
Used in Organic Synthesis:
In the field of organic synthesis, 3',6'-BIS(4,4,5,5-TETRAMETHYL-1,3,2-DIOXOBOROLAN-2-YL)-SPIRO[ISOBENZOFURAN-1(3H),9'-[9H]XANTHEN]-3-ONE serves as a key intermediate or building block for the synthesis of more complex organic molecules, leveraging its organoboron nature to facilitate various synthetic transformations.
Used in Chemical Biology Research:
3',6'-BIS(4,4,5,5-TETRAMETHYL-1,3,2-DIOXOBOROLAN-2-YL)-SPIRO[ISOBENZOFURAN-1(3H),9'-[9H]XANTHEN]-3-ONE is utilized as a research tool in chemical biology to explore its interactions with biological systems, potentially leading to the discovery of new bioactive molecules or insights into biological processes.
The synthesis and characterization of 3',6'-BIS(4,4,5,5-TETRAMETHYL-1,3,2-DIOXOBOROLAN-2-YL)-SPIRO[ISOBENZOFURAN-1(3H),9'-[9H]XANTHEN]-3-ONE are of significant interest to researchers in organic chemistry, as it represents a novel addition to the repertoire of synthetic chemists. Further investigation is necessary to uncover the full spectrum of its applications and properties.

Upstream product

• 73183-34-3 bis(pinacol)diborane 
• 85-44-9 phthalic anhydride 
• 626-02-8 3-Iodophenol 
• 87021-26-9 3',6'-dibromo-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one 
• 591-20-8 3-Bromophenol 

Relevant academic research and scientific papers

A selective, cell-permeable optical probe for hydrogen peroxide in living cells

We present the synthesis, properties, and biological applications of Peroxyfluor-1 (PF1), a new type of optical probe for intracellular imaging of hydrogen peroxide in living biological samples. PF1 utilizes a boronate deprotection mechanism to provide unprecedented selectivity and optical dynamic range for detecting H2O2 in aqueous solution over similar reactive oxygen species including superoxide, nitric oxide, tert-butyl hydroperoxide, and hydroxyl radical. We further demonstrate the value of this reagent for biological applications by imaging changes in [H2O2] in living mammalian cells. Copyright

Boronate ester cross-linked PVA hydrogels for the capture and H2O2-mediated release of active fluorophores

A new set of PVA hydrogels were formed using the boronate ester fluorescent probe PF1 and the novel boronate fluorescent probe PT1 as the covalent crosslinkers. Treatment with aqueous H2O2 allowed triggered release of the fluorescent dye accompanied by complete dissolution of the hydrogel.

Pro-fluorescent probes

The present invention provides a novel class of pro-fluorescent probes for reactive oxygen species (ROS). One exemplary probe is mitochondria peroxy yellow 1 (MitoPY1), a new type of flurophore for imaging mitochondrial H2O2 in living cells with ROS and spatial specificity. The invention also provides methods of using pro-fluorescent probes to detect analytes. One exemplary method comprises using a pro-fluorescent probe of the invention to detect an explosive.