817172-53-5

Basic information

• Product Name: 2-BIPHENYL-4-YL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE
• Synonyms: 2-BIPHENYL-4-YL-IMIDAZO[1,2-A]PYRIDINE-3-CARBALDEHYDE;2-BIPHENYL-4-YL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE
• CAS NO: 817172-53-5
• Molecular Formula: C20H14N2O
• Molecular Weight: 298.34
• Mol File: 817172-53-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-BIPHENYL-4-YL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BIPHENYL-4-YL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE(817172-53-5)
• EPA Substance Registry System: 2-BIPHENYL-4-YL-IMIDAZO[1,2-A]PYRIDINE-3-CARBOXALDEHYDE(817172-53-5)

Safety Data

• Hazardous Substances Data: 817172-53-5(Hazardous Substances Data)

Upstream product

• 38922-75-7 2-([1,1'-biphenyl]-4-yl)imidazo[1,2-a]pyridine 
• 68-12-2 N,N-dimethyl-formamide 

Relevant articles and documents

Copper- A nd DMF-mediated switchable oxidative C-H cyanation and formylation of imidazo[1,2-: A] pyridines using ammonium iodide

The cyanation and formylation of imidazo[1,2-a]pyridines were developed under copper-mediated oxidative conditions using ammonium iodide and DMF as a nontoxic combined cyano-group source and DMF as a formylation reagent. Mechanistic studies indicate that the cyanation of imidazo[1,2-a]pyridines proceeds through a two-step sequence: Initial iodination and then cyanation. The cyanation has a broad substrate scope and high functional group tolerance, and can be safely conducted on a gram scale. A novel copper-mediated formylation using the widely available DMF as the formylation reagent and environmentally friendly molecular oxygen as the oxidant has also been developed. This protocol also provided a convenient approach for the synthesis of clinically used saripidem. This journal is