817181-99-0

Basic information

• Product Name: 1-{[4'-(trifluoromethyl)-1,1'-biphenyl-2-yl]carbonyl}piperidine-4-carboxamide
• Synonyms: 1-{[4'-(trifluoromethyl)-1,1'-biphenyl-2-yl]carbonyl}piperidine-4-carboxamide
• CAS NO: 817181-99-0
• Molecular Weight: 376.378
• Mol File: 817181-99-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-{[4'-(trifluoromethyl)-1,1'-biphenyl-2-yl]carbonyl}piperidine-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{[4'-(trifluoromethyl)-1,1'-biphenyl-2-yl]carbonyl}piperidine-4-carboxamide(817181-99-0)
• EPA Substance Registry System: 1-{[4'-(trifluoromethyl)-1,1'-biphenyl-2-yl]carbonyl}piperidine-4-carboxamide(817181-99-0)

Safety Data

• Hazardous Substances Data: 817181-99-0(Hazardous Substances Data)

Upstream product

• 39546-32-2 4-carboxamidopiperidine 
• 180340-74-3 4'-trifluoromethylbiphenyl-2-carbonyl chloride 

Downstream Products

• 817182-01-7 1-{[4'-(trifluoromethyl)-1,1'-biphenyl-2-yl]carbonyl}piperidine-4-carbothioamide 

Relevant articles and documents

THIAZOLYLPIPERIDINE DERIVATIVES AS MTP INHIBITORS

The present invention relates to thiazolylpiperidine derivatives of the gen-eral formula (I): in which: A represents a radical chosen from the radicals a1 and a2 below: G represents a bond or a divalent radical chosen from the groups g1, g2 and g3 below: and R1, R2, R2’, R3, R4, R5, Y and Z are as defined in the description. Application of the compounds of the formula (I) to the treatment of hyper-triglyceridaemia, hypercholesterolaemia and dyslipidaemia.