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81720-05-0

[(1aS,1bα,5aα,6aβ)-1a,1b,2,5a,6,6a-Hexahydro-6α-hydroxy-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]6-O-α-D-galactopyranosyl-β-D-glucopyranoside, also known as Rehmannioside A, is a natural compound derived from the plant Rehmannia glutinosa. It is a complex glycoside with a unique structure consisting of a hexahydro-oxirenocyclopenta[1,2-c]pyran core, a hydroxymethyl group, and two sugar moieties, α-D-galactopyranosyl and β-D-glucopyranoside. [(1aS,1bα,5aα,6aβ)-1a,1b,2,5a,6,6a-Hexahydro-6α-hydroxy-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]6-O-α-D-galactopyranosyl-β-D-glucopyranoside has been studied for its potential therapeutic effects, particularly in the context of neurodegenerative diseases.

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  • [(1aS,1bα,5aα,6aβ)-1a,1b,2,5a,6,6a-Hexahydro-6α-hydroxy-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]6-O-α-D-galactopyranosyl-β-D-glucopyranoside

    Cas No: 81720-05-0

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  • [(1aS,1bα,5aα,6aβ)-1a,1b,2,5a,6,6a-Hexahydro-6α-hydroxy-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]6-O-α-D-galactopyranosyl-β-D-glucopyranosideCAS NO.: 81720-05-0

    Cas No: 81720-05-0

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  • 81720-05-0 Structure

  • Basic information

    1. Product Name: [(1aS,1bα,5aα,6aβ)-1a,1b,2,5a,6,6a-Hexahydro-6α-hydroxy-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]6-O-α-D-galactopyranosyl-β-D-glucopyranoside
    2. Synonyms: [(1aS,1bα,5aα,6aβ)-1a,1b,2,5a,6,6a-Hexahydro-6α-hydroxy-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]6-O-α-D-galactopyranosyl-β-D-glucopyranoside;Rehmannioside A;RhMannioside A
    3. CAS NO:81720-05-0
    4. Molecular Formula: C21H32O15
    5. Molecular Weight: 524.469
    6. EINECS: N/A
    7. Product Categories: reference substance
    8. Mol File: 81720-05-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 867 °C at 760 mmHg
    3. Flash Point: 478.1 °C
    4. Appearance: /
    5. Density: 1.78
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 12.77±0.70(Predicted)
    10. CAS DataBase Reference: [(1aS,1bα,5aα,6aβ)-1a,1b,2,5a,6,6a-Hexahydro-6α-hydroxy-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]6-O-α-D-galactopyranosyl-β-D-glucopyranoside(CAS DataBase Reference)
    11. NIST Chemistry Reference: [(1aS,1bα,5aα,6aβ)-1a,1b,2,5a,6,6a-Hexahydro-6α-hydroxy-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]6-O-α-D-galactopyranosyl-β-D-glucopyranoside(81720-05-0)
    12. EPA Substance Registry System: [(1aS,1bα,5aα,6aβ)-1a,1b,2,5a,6,6a-Hexahydro-6α-hydroxy-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]6-O-α-D-galactopyranosyl-β-D-glucopyranoside(81720-05-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 81720-05-0(Hazardous Substances Data)

81720-05-0 Usage

Uses

Used in Pharmaceutical Applications:
Rehmannioside A is used as a neuroprotective agent for the treatment of vascular dementia. It has been shown to attenuate cognitive deficits in rats with vascular dementia by suppressing oxidative stress, inflammation, and apoptosis. This suggests that Rehmannioside A may have potential as a therapeutic agent for improving cognitive function and slowing the progression of neurodegenerative diseases associated with vascular dementia.
Used in Research Applications:
Rehmannioside A is also used in scientific research to study the underlying mechanisms of neuroprotection and cognitive enhancement. Its unique structure and biological activity make it an interesting compound for investigating the complex interactions between oxidative stress, inflammation, and apoptosis in the context of neurodegenerative diseases. This research may contribute to the development of novel therapeutic strategies for the treatment of vascular dementia and other related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 81720-05-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,7,2 and 0 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 81720-05:
(7*8)+(6*1)+(5*7)+(4*2)+(3*0)+(2*0)+(1*5)=110
110 % 10 = 0
So 81720-05-0 is a valid CAS Registry Number.

81720-05-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name [(1aS,1bα,5aα,6aβ)-1a,1b,2,5a,6,6a-Hexahydro-6α-hydroxy-1aβ-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]6-O-α-D-galactopyranosyl-β-D-glucopyranoside

1.2 Other means of identification

Product number -
Other names Rehmannioside A

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81720-05-0 SDS

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