817202-84-9

Basic information

• Product Name: (R)-4-(3-dethoxy4-nitrobenzoyl)-4-aza-3'-(carboethoxy)-[6,4]-spiro-[5,6]-benzoundec-2'-ene
• Synonyms: (R)-4-(3-dethoxy4-nitrobenzoyl)-4-aza-3'-(carboethoxy)-[6,4]-spiro-[5,6]-benzoundec-2'-ene
• CAS NO: 817202-84-9
• Molecular Weight: 450.491
• Mol File: 817202-84-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-(3-dethoxy4-nitrobenzoyl)-4-aza-3'-(carboethoxy)-[6,4]-spiro-[5,6]-benzoundec-2'-ene(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-(3-dethoxy4-nitrobenzoyl)-4-aza-3'-(carboethoxy)-[6,4]-spiro-[5,6]-benzoundec-2'-ene(817202-84-9)
• EPA Substance Registry System: (R)-4-(3-dethoxy4-nitrobenzoyl)-4-aza-3'-(carboethoxy)-[6,4]-spiro-[5,6]-benzoundec-2'-ene(817202-84-9)

Safety Data

• Hazardous Substances Data: 817202-84-9(Hazardous Substances Data)

Upstream product

• 813426-23-2 (4R)-1,2,3,5-tetrahydro-spiro[4H-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid ethyl ester 
• 67579-92-4 3-methoxy-4-nitrobenzoic acid chloride 

Relevant articles and documents

Substituted spirobenzazepines

The invention is directed to nonpeptide substituted benzazepines of Formula I, which are useful as vasopressin receptor antagonists for treating conditions associated with vasopressin receptor activity such as those involving increased vascular resistance and cardiac insufficiency, including congestive heart failure, hyponatremia, and hypertension, among others disclosed. Pharmaceutical compositions comprising a compound of Formula I and methods of treating conditions such as hypertension, congestive heart failure, cardiac insufficiency, coronary vasospasm, cardiac ischemia, liver cirrhosis, hyponatremia, renal vasospasm, renal failure, diabetic nephropathy, cerebral edema, cerebral ischemia, stroke, thrombosis, or water retention are also disclosed.