817207-97-9

Upstream product

• 817207-94-6 (+)-cis-2-(3-(benzyloxy)phenyl)-1-(4-methoxyphenyl)-4-oxoazetidin-3-yl acetate 
• 817207-95-7 (3R,4S)-4-(3-(benzyloxy)phenyl)-3-hydroxy-1-(4-methoxyphenyl)azetidin-2-one 
• 1700-37-4 3-Benzyloxybenzaldehyde 
• 13154-24-0 triisopropylsilyl chloride 
• 817207-96-8 (3R,4S)-4-(3-(benzyloxy)phenyl)-1-(4-methoxyphenyl)-3-TIPS-azetidin-2-one 

Downstream Products

• 817207-98-0 4-deacetyl-4-(4-pentanoyl)-3'-desphenyl-3'-(m-benzyloxyphenyl)-7-TES-2'-TIPS-paclitaxel 
• 817207-99-1 4-deacetyl-4-(5-hexenoyl)-3'-desphenyl-3'-(m-benzyloxyphenyl)-7-TES-2'-TIPS-paclitaxel 
• 817207-78-6 (3R,4S)-1-benzoyl-4-(3-(benzyloxy)phenyl)-3-TIPS-azetidin-2-one 

Relevant academic research and scientific papers

Syntheses and bioactivities of macrocyclic paclitaxel bis-lactones

Five macrocyclic paclitaxel bis-lactones and their corresponding open chain taxoids were synthesized as models of the tubulin-binding conformation of paclitaxel. Macrocyclic lactones with a 19-21-membered ring underwent isomerization to form smaller rings