81730-50-9Relevant academic research and scientific papers
MECHANISM OF INTRAMOLECULAR CYCLIZATION IN ARYL 2-CYCLOPROPYLPHENYL SULFONES UNDER CONDITIONS OF ACID ISOMERATION
Pisanova, E. V.,Saginova, L. G.,Shabarov, Yu. S.
, p. 278 - 281 (2007/10/02)
Treatment of phenyl and p-tolyl 2-cyclopropylphenyl sulfones with concentrated sulfuric acid at 20 deg C leads to intramolecular cyclization with the formation of 10-methyl-10,11-dihydrobenzothiepin 5,5-dioxide and 8,10-dimethyl-10,11-dihydrobenzothiepin 5,5-dioxide.The reaction involves attack by the carbocation which forms at the ortho position of the adjacent benzene ring.
