81742-04-3 Usage
General Description
Hydrazinecarbodithioic acid, [1-(2-pyridinyl)propylidene]-, methyl ester is a chemical compound with the molecular formula C11H13N3S2 and a molar mass of 251.37 g/mol. It is also known by its IUPAC name as methyl 1-(2-pyridin-2-ylethylidene)carbamodithioate. Hydrazinecarbodithioic acid, [1-(2-pyridinyl)propylidene]-, methyl ester is a derivative of hydrazinecarbodithioic acid, and contains a pyridine ring and a carbodithioate functional group. It is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. Hydrazinecarbodithioic acid, [1-(2-pyridinyl)propylidene]-, methyl ester has potential applications in the field of medicinal chemistry and drug discovery due to its structural features and chemical reactivity. Additionally, it may have uses in other industries such as materials science and organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 81742-04-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,7,4 and 2 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 81742-04:
(7*8)+(6*1)+(5*7)+(4*4)+(3*2)+(2*0)+(1*4)=123
123 % 10 = 3
So 81742-04-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H13N3S2/c1-3-8(12-13-10(14)15-2)9-6-4-5-7-11-9/h4-7H,3H2,1-2H3,(H,13,14)
81742-04-3Relevant articles and documents
2-acetylpyridine thiosemicarbazones. 10. 2-Propionyl-, 2-butyryl-, and 2-(2-methylpropionyl)pyridine thiosemicarbazones as potential antimalarial agents
Klayman,Mason,Scovill
, p. 1701 - 1703 (2007/10/02)
In view of the antimalarial properties observed for many 2-acetylpyridine thiosemicarbazones, a series of N4,N4-disubstituted thiosemicarbazones derived from 2-propionyl-, 2-butyryl-, and 2-(2-methylpropionyl)pyridine was prepared for evaluation against the malaria parasite, Plasmodium berghei, in the mouse. The thiosemicarbazones were made by the reaction of methyl hydrazinecarbodithioate with a 2-acylpyridine to give the intermediate methyl 3-[1-2-pyridinyl)alkylidene]hydrazinecarbodithioates. Reaction of the latter with 3-azabicyclo[3.2.2]nonane, 1-(2-pyridinyl)piperazine, or 1H-hexahydroazepine gave the requisite thiosemicarbazones. The three thiosemicarbazones derived from 3-azabicyclo[3.2.2]nonane were most effective, the greatest potency being exhibited by 3-azabicyclo-[3.2.2]nonane-3-thiocarboxylic acid-2-[1-(2-pyridinyl)butylidene/hydrazide which cured 4/5 mice at a dose of 160 mg/kg. In contrast to the related thiosemicarbazones derived from 2-acetylpyridine, virtually no toxic effects were observed in the series described here.
