817552-55-9Relevant academic research and scientific papers
Isomerization of 2-phenacyl-1H-benzimidazole arylhydrazones to 1-aryl-5-(o-aminoanilino)-3-phenylpyrazoles by trifluoroacetylation and hydrazinolysis
Dzvinchuk,Lozinskii
, p. 845 - 849 (2005)
A convenient preparative two-stage method was developed for the isomerization of 2-phenacyl-1H-benzimidazole arylhydrazones to previously unknown 5-(o-aminoanilino)-1-aryl-3-phenylpyrazoles. The transformation scheme includes recyclization during acylation with trifluoroacetic anhydride leading to the formation of 1-aryl-3-phenyl-5-(o-trifluoroacetylaminoanilino)pyrazoles, which then undergo hydrazinolysis. 2005 Springer Science+Business Media, Inc.
