817562-96-2Relevant academic research and scientific papers
EP-2104R: A fibrin-specific gadolinium-based MRI contrast agent for detection of thrombus
Overoye-Chan, Kirsten,Koerner, Steffi,Looby, Richard J.,Kolodziej, Andrew F.,Zech, Stephan G.,Deng, Qing,Chasse, Jaclyn M.,McMurry, Thomas J.,Caravan, Peter
, p. 6025 - 6039 (2008)
Thrombus (blood clot) is implicated in a number of life threatening diseases, e.g., heart attack, stroke, pulmonary embolism. EP-2104R is an MRI contrast agent designed to detect thrombus by binding to the protein fibrin, present in all thrombi. EP-2104R
Optically pure and enriched isomers of chelating ligands and contrast agents
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Page/Page column 25; 26, (2008/06/13)
Organic chelating ligands, organic chelating ligand precursors, and metal chelates are disclosed. Methods for synthesizing the same are also described, including methods for preparing optically-enriched or optically-pure compositions of the same.
