817629-01-9Relevant academic research and scientific papers
A novel biomimetic route to the 3-acyl-5-hydroxy-3-pyrrolin-2-one and 3-acyl-3,4-epoxy-5-hydroxypyrrolidin-2-one ring systems
Snider, Barry B.,Neubert, Bobbianna J.
, p. 8952 - 8955 (2007/10/03)
Modified Moffat oxidation of alcohols 17, 22, and 25 afforded aldehydes that underwent intramolecular aldol reactions on treatment with a NaOH solution to yield 4-pyrrolin-2-ones 16, 23, and 26. Oxidation with DMDO at -40 °C provided 3-acyl-5-hydroxy-3-py
