817637-35-7

Upstream product

• 817637-39-1 (E)-methyl 3-(4-methoxybenzyloxy)acrylate 
• 105-13-5 4-Methoxybenzyl alcohol 
• 853055-27-3 (E)-3-(4-Methoxy-benzyloxy)-acrylic acid 

Downstream Products

• 817637-37-9 (4S,5S)-4-(4-Methoxy-benzyloxy)-5-methyl-5-(4-methyl-pent-3-enyl)-dihydro-furan-2-one 
• 1197006-45-3 (E)-4-methoxybenzyl 4-oxo-4-((S)-2-oxo-4-phenyloxazolidin-3-yl)but-2-enoate 

Relevant academic research and scientific papers

Nitrile Ylides: Diastereoselective cycloadditions using chiral oxzolidinones without Lewis acid

"Chemical Equation Presented" Lewis acid complexation Is generally required for chiral-auxiliary-controlled stereoselectivity, and chiral Lewis acid catalysis Is frequently optimal for Introducing asymmetry. In this work, we show that nitrlle ylide cycloadditions to electron-poor acceptors attached to chiral auxiliaries proceed In high yield and stereoselectivity in the absence of Lewis acids. In contrast, chiral Lewis acids are Inferior In these cycloadditions.

The samarium(II)-mediated intermolecular couplings of ketones and β-alkoxyacrylates: A short asymmetric synthesis of an antifungal γ-butyrolactone

The samarium(II) iodide-mediated coupling of ketones with β-alkoxyacrylates gives β-hydroxy-γ-butyrolactones in moderate yield. The process has been applied to the asymmetric synthesis of an antifungal, γ-butyrolactone natural product.