81784-18-1Relevant articles and documents
Enantioselective synthesis of herbertane sesquiterpenes: Synthesis of (-)-α-formylherbertenol
Abad, Antonio,Agullo, Consuelo,Cunat, Ana C.,Perni, Remedios H.
, p. 1607 - 1615 (2007/10/03)
The synthesis of 4-hydroxy-3-[(1S)-1,2,2-trimethylcyclopentyl]benzaldehyde [(-)-α-formylherbertenol 1], a herbertane-type sesquiterpene isolated from the leafy liverwort Herberta adunca, from β-cyclogeraniol is described. The synthesis is based on the previously described preparation of an enantiopure 1,2,2-trimethylcyclopentane synthon from which the characteristic aromatic moiety of 1 is elaborated, using a Robinson annulation and a palladium-catalysed methoxycarbonylation of an aryl triflate as key synthetic steps. The synthesis of the natural sesquiterpene (-)-α-herbertenol, also a natural sequiterpene, using the same methodology is also described. Copyright (C) 2000 Elsevier Science Ltd.
THREE NEW SESQUITERPENE PHENOLS OF THE ENT-HERBERTANE CLASS FROM THE LIVERWORT HERBERTA ADUNCA
Matsuo, Akihiko,Yuki, Shunji,Nakayama, Mitsuru,Hayashi, Shuichi
, p. 463 - 466 (2007/10/02)
Three sesquiterpene phenols with an ent-herberatne skeleton have been isolated from the liverworth Herberta adunca, and the alucidation of their structures and absolue configurations has been achieved on the basis of the chemical and spectral evidence.