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3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is a chemical compound that consists of adenosine, a nucleoside and a building block for RNA, with 3'-O-tert-butyldimethylsilyl and 5'-O-DMT protecting groups. These protecting groups are used in organic synthesis to shield specific functional groups during reactions, enabling selective manipulations of the molecule and preventing unwanted side reactions.

81794-12-9

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81794-12-9 Usage

Uses

Used in Organic Synthesis:
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is used as a precursor in the synthesis of nucleic acid analogs, where the protecting groups allow for selective reactions and the controlled formation of complex molecules.
Used in Biochemical Research:
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine serves as a research tool in biochemical studies related to nucleosides and nucleic acids, aiding in the investigation of their structure, function, and interactions within biological systems.

Check Digit Verification of cas no

The CAS Registry Mumber 81794-12-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,7,9 and 4 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 81794-12:
(7*8)+(6*1)+(5*7)+(4*9)+(3*4)+(2*1)+(1*2)=149
149 % 10 = 9
So 81794-12-9 is a valid CAS Registry Number.

81794-12-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-

1.2 Other means of identification

Product number -
Other names 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81794-12-9 SDS

81794-12-9Downstream Products

81794-12-9Relevant academic research and scientific papers

New catalists and procedures for the dimethoxytritylation and selective silylation of ribonucleosides

Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.

, p. 1106 - 1113 (2007/10/02)

Procedures have been developed for the selective formation of (a) 2',5'-silylated ribonucleosides and (b) 3',5'-silylated ribonucleosides.These procedures also permit the selective silylation at either the 2'- or 3'-position of dimethoxytritylated ribonuc

HIGH YIELD SELECTIVE 3'-SILYLATION OF RIBONUCLEOSIDES

Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.

, p. 5243 - 5246 (2007/10/02)

Prucedures have been developed which permit the highly selective silylation of the 3'-hydroxyl of ribonucleosides to produce 3',5'-diprotected derivatives in high yields.

NITRATE ION AS CATALYST FOR SELECTIVE SILYLATIONS OF NUCLEOSIDES

Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.

, p. 4775 - 4778 (2007/10/02)

Nitrate ion has been found to have a remarkable effect on the selectivity of silylation of ribonucleosides using the t-butyldimethylsilyl group.

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