81794-13-0 Usage
Uses
Used in Organic Synthesis:
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is used as a key intermediate in organic synthesis for the production of RNA molecules. Its unique structure and reactivity allow for selective deprotection and further manipulation in chemical reactions, facilitating the synthesis of complex RNA structures.
Used in Research and Biotechnological Applications:
In the fields of research and biotechnology, 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is employed as a building block for the creation of RNA molecules. Its protective groups on the 2'-O and 5'-O positions ensure the stability and integrity of the adenosine molecule during the synthesis process, making it an essential component in the development of RNA-based therapeutics and diagnostic tools.
Used in Nucleic Acid Chemistry:
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine plays a crucial role in nucleic acid chemistry, where it is used as a versatile compound for the study and manipulation of RNA structures. Its protective groups allow for selective deprotection and further chemical reactions, enabling researchers to explore the properties and functions of RNA molecules in greater detail.
Used in Molecular Biology:
In molecular biology, 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine is utilized as a component in the synthesis of RNA molecules for various applications, such as gene expression studies, functional analysis of RNA elements, and the development of RNA-based drugs and vaccines. Its protective groups ensure the stability and reactivity of the adenosine molecule, making it an indispensable tool in molecular biology research.
Check Digit Verification of cas no
The CAS Registry Mumber 81794-13-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,7,9 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 81794-13:
(7*8)+(6*1)+(5*7)+(4*9)+(3*4)+(2*1)+(1*3)=150
150 % 10 = 0
So 81794-13-0 is a valid CAS Registry Number.
81794-13-0Relevant academic research and scientific papers
Preparation of deoxynucleosides
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Page column 16-17, (2008/06/13)
Methods for preparing deoxynucleosides from their corresponding ribonucleosides by forming 3-tert-butylphenoxythiocarbonylderivatives of the ribonucleosides and subsequently effecting radical deoxygenation reactions at the carbon atoms to be deoxygenated.
New catalists and procedures for the dimethoxytritylation and selective silylation of ribonucleosides
Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.
, p. 1106 - 1113 (2007/10/02)
Procedures have been developed for the selective formation of (a) 2',5'-silylated ribonucleosides and (b) 3',5'-silylated ribonucleosides.These procedures also permit the selective silylation at either the 2'- or 3'-position of dimethoxytritylated ribonuc
HIGH YIELD SELECTIVE 3'-SILYLATION OF RIBONUCLEOSIDES
Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.
, p. 5243 - 5246 (2007/10/02)
Prucedures have been developed which permit the highly selective silylation of the 3'-hydroxyl of ribonucleosides to produce 3',5'-diprotected derivatives in high yields.
NITRATE ION AS CATALYST FOR SELECTIVE SILYLATIONS OF NUCLEOSIDES
Hakimelahi, Gholam H.,Proba, Zbigniew A.,Ogilvie, Kelvin K.
, p. 4775 - 4778 (2007/10/02)
Nitrate ion has been found to have a remarkable effect on the selectivity of silylation of ribonucleosides using the t-butyldimethylsilyl group.
