81795-54-2Relevant academic research and scientific papers
Microwave-enhanced bismuth triflate-catalyzed epoxide opening with aliphatic amines
Ollevier, Thierry,Nadeau, Etienne
, p. 1546 - 1550 (2008/09/19)
In the presence of a catalytic amount of Bi(OTf)3·4H2O and under microwave irradiation, neat mixtures of epoxides and amines afforded smoothly the corresponding 2-amino alcohols. A wide variety of aliphatic amines were reacted with cycloalkene oxide, styrene oxide, and stilbene oxide. The reaction proceeded rapidly and afforded the 2-amino alcohols in high up to quantitative yields. All products could be obtained without aqueous work-up by simple filtration.
The Reaction between trans-2-Alkylaminocycloalkanols and Formaldehyde
Barkworth, Peter M. R.,Crabb, Trevor A.
, p. 260 - 264 (2007/10/02)
trans-2-Alkylaminocyclohexanols and trans-2-alkylaminocycloheptanols condense with formaldehyde to give perhydrocycloalkanooxazoles, whereas trans-2-alkylaminocyclopentanols give rise to perhydrocyclopentanodioxazepines.The two types of ring systems are characterized by differing proton-proton geminal coupling constants and 13C NMR parameters.
