81820-18-0

Upstream product

• 17630-76-1 5-chloroindole 2,3-dione 
• 75129-75-8 N‐(4‐(2‐hydrazinyl‐2‐oxoethoxy)phenyl) acetamide 

Downstream Products

• 81820-12-4 N-{4-[5-Chloro-2-oxo-1-piperidin-1-ylmethyl-1,2-dihydro-indol-(3Z)-ylidene-hydrazinocarbonylmethoxy]-phenyl}-acetamide 
• 81820-15-7 N-{4-[5-Chloro-2-oxo-1-(4-phenyl-piperazin-1-ylmethyl)-1,2-dihydro-indol-(3Z)-ylidene-hydrazinocarbonylmethoxy]-phenyl}-acetamide 
• 81820-14-6 N-{4-[5-Chloro-1-(4-methyl-piperazin-1-ylmethyl)-2-oxo-1,2-dihydro-indol-(3Z)-ylidene-hydrazinocarbonylmethoxy]-phenyl}-acetamide 
• 81820-13-5 N-{4-[5-Chloro-1-morpholin-4-ylmethyl-2-oxo-1,2-dihydro-indol-(3Z)-ylidene-hydrazinocarbonylmethoxy]-phenyl}-acetamide 

Relevant academic research and scientific papers

Synthesis and CNS Activity of 1,5-Disubstituted -3-(4'-acetamidophenoxyacetylhydrazono)indolin-2-ones

5-Substituted-indoline-2,3-diones on condensation with 4-acetamidophenoxyacetylhydrazine give 5-substituted-3-(4'-acetamidophenoxyacetylhydrazono)indolin-2-ones (I) which undergo Mannich reaction with secondary amines, to give 1,5-disubstituted-3-(4'-acet