81841-56-7

Upstream product

• 76-83-5 trityl chloride 
• 33493-69-5 (1R,1'R)-1,1'-[(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]diethane-1,2-diol 
• 3969-84-4 3,4-di-O-isopropylidene-D-mannitol 
• 3969-59-3 mannitol triacetonide 
• 38145-93-6 (S)-1-((4R,4'R,5R)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolan)-5-yl)ethane-1,2-diol 
• 4239-88-7 O¹,O²;O³,O⁴;O⁵,O⁶-triisopropylidene-D-glucitol 

Downstream Products

• 81841-57-8 3,4-disoprpylidene-1,6-di-O-triphenylmethyl-D-mannitol diacetate 
• 876062-94-1 2,5-di-O-benzoyl-3,4-O-isopropylidene-1,6-di-O-trityl-D-mannitol 
• 189702-29-2 Benzoic acid (1R,3R)-4-benzyloxy-1-((R)-2-benzyloxy-1-methoxy-ethyl)-3-methoxy-2-oxo-butyl ester 
• 1053653-16-9 Benzoic acid (1S,2R,3R)-4-benzyloxy-1-((R)-2-benzyloxy-1-methoxy-ethyl)-2-hydroxy-3-methoxy-butyl ester 
• 90126-18-4 (4R,5R)-4,5-Bis-((R)-2-benzyloxy-1-methoxy-ethyl)-2,2-dimethyl-[1,3]dioxolane 
• 90126-25-3 1,6-dibenzyl-2,5-dimethyl-D-mannitol 
• 90126-13-9 O³,O⁴-isopropylidene-O²,O⁵-dimethyl-O¹,O⁶-ditrityl-D-mannitol 

Relevant academic research and scientific papers

POLYSULFATED GLYCOSIDES AND SALTS THEREOF

The invention relates to polysulfated glycosides of formula (I), the pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions containing these compounds as active ingredients. Furthermore the invention provides a method of preventing, treating or alleviating the symptoms of acute and chronic inflammatory disorders of the airways of mammals - including asthma and asthma-related pathologies.

Diastereoselective Grignard Additions to O-Protected Polyhydroxylated Ketones: A Reaction Controlled by Groundstate Conformation?

The O-protected polyhydroxy ketones 9-14 and 39, 42 add σ-type Grignard reagents with >90:10 stereoselectivity to give the 3,4-syn-adducts 17-22 and 43, 45, respectively, as the major diastereomers (Tables 1 and 2). The stereoselectivity is interpreted in terms of early transition states which are very close to the groundstate conformations shown in Figure 6 and 7. These demonstrate that the "top face" of the carbonyl group is much less shielded than the "bottom" face, Complexation phenomena are of minor importance. It is also shown that the classical transition state models (Felkin-Anh or chelate Cram) are not applicable to polyoxygenated ketones.

BRANCHED CHAIN SUGARS. XXVIII. SYNTHESIS OF 2-C-METHYL-L-GLYCERALDEHYDE, 2-C-METHYL-D-ERYTHROSE, AND 3-C-METHYL-L-ERYTHROSE DERIVATIVES

As synthons for the synthesis of bicyclomycin, the title compounds were derived from 1,2:5,6-di-O-isopropylidene-3-C-methyl-α-D-allofuranose bythe descendent method.