81850-14-8Relevant academic research and scientific papers
THIOSTANNANE-MEDIATED PREPARATION OF γ-ALKOXYALLYL SULFIDES; EFFICIENT β-ALKYLATION OF α,β-UNSATURATED ALDEHYDES
Sato, Tsuneo,Okazaki, Hiroshi,Otera, Junzo,Nozaki, Hitosi
, p. 2979 - 2982 (2007/10/02)
The title β-alkylation is achieved through a sequence of sulfenylation of α-enal acetals, t-BuLi-promoted alkylation, and oxidative hydrolysis.
Heteroatom-Directed Allylic Substitution and Rearrangement Reactions
Hagen, James P.,Harris, Joseph J.,Lakin, Danielle
, p. 782 - 787 (2007/10/02)
Alcoholic, phenolic, and thiolic nucleophiles attack 3-chloro-1-methoxypropene (1) exclusively at C-1 in the presence of N,N-diisopropylethylamine.The reaction is formally a high regioselective SN2' process.Some of the oxygen nucleophiles (e.g.
Stereoselective Synthesis of Alcohols, XX. - Diastereoselective Addition of γ-Alkoxyallylboronates to Aldehydes
Hoffmann, Reinhard W.,Kemper, Bruno,Metternich, Rainer,Lehmeier, Thomas
, p. 2246 - 2260 (2007/10/02)
Both the (Z)- and (E)-γ-alkoxysubstituted allylboronates 1 and 3 have been prepared.They add to aldehydes with a diastereoselectivity generally exceeding 90percent to give the syn-(2) and anti-diol derivatives 4, respectively.The structure of one of these adducts has been established by conversion into exo-brevicomin (26).
