81851-76-5Relevant academic research and scientific papers
Symmetrical Alkoxysilyl Ethers. A New Class of Alcohol-Protecting Groups. Preparation of tert-Butoxydiphenylsilyl Ethers
Gillard, John W.,Fortin, Rejean,Morton, Howard E.,Yoakim, Christiane,Quesnelle, Claude A.,at al.
, p. 2602 - 2608 (2007/10/02)
The preparation and evaluation of a new class of alcohol-protecting groups, the alkoxydiphenylsilyl ethers, are described.In particular, tert-butoxydiphenylsilyl ethers, which can be formed from primary, secondary, or tertiary alcohols and tert-butoxydiphenylsilyl chloride, offer the useful synthetic properties of acid stability and high fluoride reactivity.Opportunities for selective silyl group cleavage are highlighted.
