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1,3-Benzodioxole-5,6-diamine dihydrochloride is an organic compound characterized by a benzodioxole ring with two amine groups at the 5,6-positions and two hydrochloride ions. It is a light brown solid and is known for its high sensitivity as a reagent for α-keto acids and its use as a fluorometric labeling reagent.

81864-15-5

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81864-15-5 Usage

Uses

Used in Chemical Analysis:
1,3-Benzodioxole-5,6-diamine dihydrochloride is used as a highly sensitive reagent for the detection and analysis of α-keto acids. Its high sensitivity makes it a valuable tool in various analytical techniques.
Used in Fluorescence Labeling:
1,3-Benzodioxole-5,6-diamine dihydrochloride serves as a fluorometric labeling reagent, allowing for the fluorescent tagging of specific molecules or compounds. This is particularly useful in research and diagnostic applications where the detection and visualization of target molecules are required.
Used in Dyes and Metabolites:
1,3-Benzodioxole-5,6-diamine dihydrochloride is also utilized in the development of dyes and metabolites, where its unique chemical properties contribute to the creation of novel compounds with specific characteristics and applications.
Used in Pharmaceutical Industry:
1,3-Benzodioxole-5,6-diamine dihydrochloride can be employed as an intermediate in the synthesis of various pharmaceutical compounds, given its reactive amine groups and the potential for further chemical modifications.
Used in Research and Development:
In the field of research and development, 1,3-benzodioxole-5,6-diamine dihydrochloride is used for the exploration of new chemical reactions, the synthesis of novel compounds, and the investigation of its potential applications in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 81864-15-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,8,6 and 4 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 81864-15:
(7*8)+(6*1)+(5*8)+(4*6)+(3*4)+(2*1)+(1*5)=145
145 % 10 = 5
So 81864-15-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N2O2.2ClH/c8-4-1-6-7(2-5(4)9)11-3-10-6;;/h1-2H,3,8-9H2;2*1H

81864-15-5 Well-known Company Product Price

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  • Sigma-Aldrich

  • (66807)  4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride  BioReagent, suitable for fluorescence, ≥99.0% (HPLC)

  • 81864-15-5

  • 66807-10MG

  • 1,022.58CNY

  • Detail
  • Sigma-Aldrich

  • (66807)  4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride  BioReagent, suitable for fluorescence, ≥99.0% (HPLC)

  • 81864-15-5

  • 66807-50MG

  • 3,352.05CNY

  • Detail
  • Sigma-Aldrich

  • (D4784)  4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride  Fluorogenic reagent

  • 81864-15-5

  • D4784-10MG

  • 1,060.02CNY

  • Detail
  • Sigma-Aldrich

  • (D4784)  4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride  Fluorogenic reagent

  • 81864-15-5

  • D4784-50MG

  • 3,123.90CNY

  • Detail
  • Sigma-Aldrich

  • (D4784)  4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride  Fluorogenic reagent

  • 81864-15-5

  • D4784-100MG

  • 5,390.19CNY

  • Detail

81864-15-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,2-Diamino-4,5-methylenedioxybenzene, Dihydrochloride

1.2 Other means of identification

Product number -
Other names 1,3-benzodioxole-5,6-diamine,dihydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:81864-15-5 SDS

81864-15-5Relevant academic research and scientific papers

1,2-Diamino-4,5-methylenedioxybenzene as a Highly Sensitive Fluorogenic Reagent for α-Keto Acids

Nakamura, Masaru,Hara, Shuuji,Yamaguchi, Masatoshi,Takemori, Yasuyo,Ohkura, Yosuke

, p. 687 - 692 (2007/10/02)

The reactivity of pyruvic acid with 1,2-diaminobenzenes was investigated as part of a survay of fluorogenic reagents for α-keto acids of biological importance.Of eight 1,2-diaminobenzenes tested, 1,2-diamino-4,5-methylenedioxybenzene was found to be the best reagent in terms of sensitivity and reactivity.The reagent reacts with α-keto acids in an acidic solution to produce the corresponding fluorescent derivatives, which fluorescent most intensely in a neutral medium.The derivatives of ten α-keto acids can be separeted within 18 min by reversed-phase high-performance liquid chromatography with isocratic elution.The detection limits for the acids are at femtomole levels for an injection volume of 10 μl.The fluorescent product from pyruvic acid was characterized as 3-methyl-6,7-methylenedioxy-2(1H)-quinoxalinone.The fluorescence properties of the product are also described.

Imidazole derivatives

-

, (2008/06/13)

Tricyclic imidazole derivatives of the formula STR1 wherein R1 is 2-pyridyl optionally substituted by lower alkyl or lower alkoxy, n is the integer 0 or 1, R2 is hydrogen or lower alkyl, R3 and R4, independently, are hydrogen or lower alkyl, A is a group of the formula STR2 m is the integer 2 or 3, R5, R6, R7 and R8, independently, are hydrogen or lower alkyl, and R9 is hydrogen and R10 is hydrogen or lower alkyl or R9 and R10 taken together are oxo, provided that at least one of R3 and R4 is lower alkyl when A is a group of the formula and their pharmaceutically acceptable acid addition salts. The compounds of formula I inhibit gastric acid secretion and prevent the formation of gastric ulcers.

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