81884-58-4

Upstream product

• 133150-11-5 4-benzyl-5-benzylimino-2-phenyl-1,2,4-thiadiazolidin-3-one 
• 3173-56-6 benzyl isothiocyanate 
• 6320-65-6 4-methyl-5-(methylimino)-1,2,4-dithiazolidine-3-one 
• 100-46-9 benzylamine 

Relevant academic research and scientific papers

Cycloaddition-Elimination Reactions of 5-Imino-1,2,4-dithiazolidin-3-ones with Heterocumulenes

5-Benzylimino-1,2,4-dithiazolidin-3-one (2a) reacts with heterocumulenes (isocyanates, isothiocyanates, ketenes) with elimination of carbonyl sulfide, yielding the heterocycles 6-8.The thiadiazolidine 6a, obtained from 2a and phenyl isocyanate, underwent similar reactions but under milder conditions, indicating that phenyl isocyanate is a better leaving group than carbonyl sulfide.

Heterocyclic Compounds: Sulphur as a Potential Oxidant: Preparation of 5-Alkyl/arylimino-2,4-dialkyl/aryl-3-thio/oxo-1,2,4-thiadiazolidines

Some interesting observations involving reaction of excess of benzylamine and isoperthiocyanic acid (Ia), the so-called isothiocyanate sulphides (Ib-If) and isothiocyanate oxides (II) have been reported.In these reactions 5-alkyl/arylimino-2,4-dialkyl/aryl-3-thio-1,2,4-thiadiazolidines (III) and 5-arylimino-2,4-dialkyl/aryl-3-oxo-1,2,4-thiadiazolidines (VI) have been isolated.In all these reactions, elemental sulphur initially formed acts as a potential oxidant in the oxidative cyclisation of intermediates, viz., 2,4-dithiobiurets (IV) and 2-thiobiurets (VII).