819057-57-3Relevant academic research and scientific papers
3-Amino-benzo[d]isoxazoles as novel multitargeted inhibitors of receptor tyrosine kinases
Ji, Zhiqin,Ahmed, Asma A.,Albert, Daniel H.,Bouska, Jennifer J.,Bousquet, Peter F.,Cunha, George A.,Diaz, Gilbert,Glaser, Keith B.,Guo, Jun,Harris, Christopher M.,Li, Junling,Marcotte, Patrick A.,Moskey, Maria D.,Oie, Tetsuro,Pease, Lori,Soni, Nirupama B.,Stewart, Kent D.,Davidsen, Steven K.,Michaelides, Michael R.
, p. 1231 - 1241 (2008/12/20)
A series of benzoisoxazoles and benzoisothiazoles have been synthesized and evaluated as inhibitors of receptor tyrosine kinases (RTKs). Structure-activity relationship studies led to the identification of 3-amino benzo[d]isoxazoles, incorporating a N,N′-
