819078-82-5Relevant articles and documents
Identified a morpholinyl-4-piperidinylacetic acid derivative as a potent oral active VLA-4 antagonist
Chiba, Jun,MacHinaga, Nobuo,Takashi, Tohru,Ejima, Akio,Takayama, Gensuke,Yokoyama, Mika,Nakayama, Atsushi,Baldwin, John J.,McDonald, Edward,Saionz, Kurt W.,Swanson, Robert,Hussain, Zahid,Wong, Angela
, p. 41 - 45 (2005)
An investigation into the structure-activitiy relationship of a lead compound led to the identification of a novel series of piperidinylacetic acid, piperazinylacetic acid, and 4-aminobenzoic acid derivatives as potent VLA-4 antagonists with low nanomolar
