81925-25-9

Basic information

• Product Name: 2-(E)-(1-buta-1,3-dienyl)-1-(E)-(3-prop-2-en-1-al)cyclohexanol
• Synonyms: 2-(E)-(1-buta-1,3-dienyl)-1-(E)-(3-prop-2-en-1-al)cyclohexanol
• CAS NO: 81925-25-9
• Molecular Weight: 206.285
• Mol File: 81925-25-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(E)-(1-buta-1,3-dienyl)-1-(E)-(3-prop-2-en-1-al)cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(E)-(1-buta-1,3-dienyl)-1-(E)-(3-prop-2-en-1-al)cyclohexanol(81925-25-9)
• EPA Substance Registry System: 2-(E)-(1-buta-1,3-dienyl)-1-(E)-(3-prop-2-en-1-al)cyclohexanol(81925-25-9)

Safety Data

• Hazardous Substances Data: 81925-25-9(Hazardous Substances Data)

Upstream product

• 31805-84-2 1,3-bis(methylthio)-2-methoxypropane 
• 78845-11-1 1-(1,3-bis(methylthio)prop-2-enyl)-2-(1-buta-1,3-dienyl)cyclohexanol 

Downstream Products

• 78845-08-6 1,2-(E,E)-di(1-buta-1,3-dienyl)cyclohexanol 

Relevant articles and documents

MACROEXPANSION METHODOLOGY; MEDIUM RING SYNTHESIS BASED ON AN EIGHT UNIT RING EXPANSION PROCESS

Treatment of 1,2-(E,E)-di(1-buta-1,3-dienyl)cyclohexanol (21) with potassium hydride in tetrahydrofuran at room temperature resulted in the facile formation of a 14-membered ring dienolate which on kinetic protonation provided cyclotetradeca-3,5,7-trien-1-one.This novel rearrangement which provides the basis for an efficient, eight unit ring expansion method was also observed when 5,8-dimethyl-5-hydroxy-1,3,7,9-decapentaene (28), the acyclic analogue of 21, was treatad with potassium hydride in tetrahydrofuran.Methodology for the preparation of 21 and 28 including the preparation of 1-lithio-1,3-butadiene is also described.