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[6-(4-Bromo-phenyl)-3-phenyl-imidazo[2,1-b]thiazol-2-yl]-acetic acid is a complex organic compound with the molecular formula C20H14BrN2OS2. It features a 2-imidazo[2,1-b]thiazolyl core, which is substituted with a 4-bromophenyl group at the 6th position and a phenyl group at the 3rd position. The molecule also contains an acetic acid group attached to the imidazo[2,1-b]thiazol-2-yl moiety. [6-(4-Bromo-phenyl)-3-phenyl-imidazo[2,1-b]thiazol-2-yl]-acetic acid is known for its potential applications in pharmaceutical research, particularly as a precursor or intermediate in the synthesis of various biologically active molecules. Its unique structure, which includes a halogenated aromatic ring and a heterocyclic core, may contribute to its interaction with specific biological targets, making it a subject of interest in drug development.

81949-99-7

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81949-99-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 81949-99-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,9,4 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 81949-99:
(7*8)+(6*1)+(5*9)+(4*4)+(3*9)+(2*9)+(1*9)=177
177 % 10 = 7
So 81949-99-7 is a valid CAS Registry Number.

81949-99-7Downstream Products

81949-99-7Relevant academic research and scientific papers

Synthesis and Anthiinflammatory Activity of Some Arylimidazothiazolyl- and Arylimidazobenzothiazolyl-acetic Acids

Sawhney, S. N.,Kodali, Dharma R.,Dhindsa, G. S.,Singh, S. P.

, p. 134 - 138 (2007/10/02)

Three series of the title compounds, imidazothiazolyl-, imidazobenzothiazolyl- and imidazobenzothiazolylaryl-acetic acids (II,III and IV) have been synthesised for evaluation as potential anti-inflammatory agents.Compounds II have been synthesised by condensing ethyl (2-amino-4-aryl-5-thiazolyl)acetate (VI) with phenacyl bromides followed by hydrolysis of the resultant esters (VII).III are obtained by the condensatiion of ethyl 2-aminobenzothiazole-6-acetate with phenacyl bromides followed by hydrolysis of the resultant esters (IX).Compound IV result from the treatment of 2-aminobenzothiazoles with ethyl 4(ω-bromoacetylphenyl)acetate (XI) followed by hydrolysis of the esters (XII).Some of the title compounds show good antiinflammatory activity.

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