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[6-(4-Fluoro-phenyl)-3-phenyl-imidazo[2,1-b]thiazol-2-yl]-acetic acid is a complex organic compound with the molecular formula C21H14FN2OS2. It features a 2-imidazo[2,1-b]thiazol-2-yl core structure, with a 4-fluoro-phenyl group at position 6 and a phenyl group at position 3. The molecule also contains an acetic acid functional group, which is attached to the imidazo[2,1-b]thiazol-2-yl core. [6-(4-Fluoro-phenyl)-3-phenyl-imidazo[2,1-b]thiazol-2-yl]-acetic acid is known for its potential applications in medicinal chemistry, particularly as a precursor or intermediate in the synthesis of various pharmaceuticals. Its unique structure and properties make it a subject of interest for researchers exploring new drug candidates and therapeutic agents.

81950-01-8

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81950-01-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 81950-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,1,9,5 and 0 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 81950-01:
(7*8)+(6*1)+(5*9)+(4*5)+(3*0)+(2*0)+(1*1)=128
128 % 10 = 8
So 81950-01-8 is a valid CAS Registry Number.

81950-01-8Downstream Products

81950-01-8Relevant academic research and scientific papers

Synthesis and Anthiinflammatory Activity of Some Arylimidazothiazolyl- and Arylimidazobenzothiazolyl-acetic Acids

Sawhney, S. N.,Kodali, Dharma R.,Dhindsa, G. S.,Singh, S. P.

, p. 134 - 138 (2007/10/02)

Three series of the title compounds, imidazothiazolyl-, imidazobenzothiazolyl- and imidazobenzothiazolylaryl-acetic acids (II,III and IV) have been synthesised for evaluation as potential anti-inflammatory agents.Compounds II have been synthesised by condensing ethyl (2-amino-4-aryl-5-thiazolyl)acetate (VI) with phenacyl bromides followed by hydrolysis of the resultant esters (VII).III are obtained by the condensatiion of ethyl 2-aminobenzothiazole-6-acetate with phenacyl bromides followed by hydrolysis of the resultant esters (IX).Compound IV result from the treatment of 2-aminobenzothiazoles with ethyl 4(ω-bromoacetylphenyl)acetate (XI) followed by hydrolysis of the esters (XII).Some of the title compounds show good antiinflammatory activity.

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