81975-31-7

Upstream product

• 109547-84-4 (Z)-3-Thiophen-2-yl-2-p-tolyliminomethyleneamino-acrylic acid ethyl ester 
• 1056976-66-9 ethyl (Z)-2-azido-3-(2-thienyl)prop-2-enoate 
• 13250-83-4 2,3-Thiophenedicarbaldehyde 3-(Ethylene acetal) 
• 1315574-37-8 ethyl 2-azido-3-[3-(1,3-dioxolan-2-yl)-2-thienyl]propenoate 
• 60248-98-8 Ethyl 4,5-dihydro-4-oxothieno<3,2-c>pyridine-6-carboxylate 
• 109547-78-6 C₂₇H₂₄NO₂PS 
• 622-58-2 p-Tolylisocyanate 
• 81975-29-3 Ethyl 4-chlorothieno<3,2-c>pyridine-6-carboxylate 
• 106-49-0 p-toluidine 

Relevant academic research and scientific papers

Retro-Cheletropic ene reactions with 2-carbena-1,3-dioxolane as chelefuge

N[β-(Hetero)arylvinyl] ketenimines and carbodiimides bearing adequately positioned 1,3-dioxolane functions experience a new class of tandem process consisting of a 6π electrocyclic ring closure followed by a rare retro-cheletropic ene reaction, the extrusion of 2-carbena-1,3-dioxolane. This mechanistic sequence is supported by a computational study using DFT methods, showing that the simultaneous recovery of aromaticity at two rings is the clue for the low energy barrier of the retro-cheletropic step. Moreover, the highly exergonic decomposition of 2-carbena-1,3-dioxolane into CO2 plus ethylene contribute to the success of the tandem sequences.

An Efficient Iminophosphorane-Mediated Synthesis of Thienopyridine, Thienopyridine and Furopyridine Derivatives

A number of thienopyridines 4, thienopyridines 7 and furopyridines 11 derivatives have been prepared by reaction of the appropriate iminophosphorane, available from ethyl azidoheteroarylacrylates and triphenylphosphine, with aromatic

Reactions of Ethyl 4,5-Dihydro-4-oxothienopyridine-6-carboxylate : Synthesis of New Thienopyridine Derivatives and Thienopyridino-as-triazines

Ethyl 4,5-dihydro-4-oxothienopyridine-6-carboxylate (I) has been used as the starting compound for the synthesis of some new thienopyridines and thienopyrido-as-triazines.