81976-52-5Relevant academic research and scientific papers
Effect of flavonol derivatives on the carrageenin-induced paw edema in the rat and inhibition of cyclooxygenase-1 and 5-lipoxygenase in vitro.
Sobottka,Werner,Blaschke,Kiefer,Nowe,Dannhardt,Schapoval,Schenkel,Scriba
, p. 205 - 210 (2000)
Alkoxyflavonols were synthesized by the Algar-Flynn-Oyamada (AFO) cyclization of chalcones. Hydroxyflavonols were prepared by dealkylation of methoxyflavonols by refluxing in hydroiodic acid. The alkoxyflavonols 3-hydroxy-2-(2,3,4-trimethoxyphenyl)-4H-chr
Structural and spectroscopic analysis and evaluation of cytotoxic activity of 2-hydroxychalcones against human cancer cell lines
Almeida-Neto, Francisco W. Q.,Bandeira, Paulo N.,Barreto, Ant?nio C. H.,Barros-Nepomuceno, Francisco W. A.,Juli?o, Murilo S. S.,Leal, Antonio L. A. B.,Marinho, Emmanuel S.,Pessoa, Claudia,Pinheiro, Daniel P.,Teixeira, Alexandre M. R.,da Silva, Priscila T.,de Lima-Neto, Pedro,de Paiva, Aldeneide S.,dos Santos, Hélcio S.
, (2021/07/28)
Chalcones and their derivatives exhibit a broad spectrum of pharmacological activities, including antiproliferative activities. Accordingly, they are deemed robust anticancer candidates for cytotoxicity assays. Herein, we synthesized and characterized fou
Microwave assisted synthesis, characterization, molecular docking and pharmacological activities of some new 2′-hydroxychalcone derivatives
Bhuiyan, M. Mosharef H.,Knock, Md Nazmul Hassan,Sadrul Amin, Hossain Md,Sanaullah, A. F. M.,Shumi, Wahhida,Uddin, Mohammad Nasir,Uzzaman, Monir
, (2020/01/25)
Synthesis of six new α, β-unsaturated carbonyl compounds (2′-hydroxychalcones) from 2′-hydroxyacethophenone and aromatic aldehyde derivatives under microwave condition has been described due to their pharmaceutical interest. They were characterized by FTI
