819799-84-3

Upstream product

• 819799-82-1 (2R)-(1-benzyloxy-4-bromo-3,3,4,4-tetrafluoro)but-2-yl formate 
• 819799-79-6 (2R)-1-benzyloxy-4-bromo-3,3,4,4-tetrafluorobutan-2-ol 

Relevant academic research and scientific papers

Enantioselective synthesis of tetrafluorinated ribose and fructose

A perfluoroalkylidene lithium mediated cyclisation approach for the enantioselective synthesis of a tetrafluorinated aldose (ribose) and of a tetrafluorinated ketose (fructose), both in the furanose and in the pyranose form, is described.

Enantioselective synthesis of tetrafluoroethylene-containing monosaccharides

A Sharpless asymmetric dihydroxylation of the commercially available building block 1 affords the common chiral intermediate 2 for the synthesis of the fluoridated monosaccharides 3-5 (Bn=benzyl).