81995-18-8

Upstream product

• 502-44-3 hexahydro-2H-oxepin-2-one 
• 19493-09-5 Methylenetriphenylphosphorane 
• 1779-49-3 Methyltriphenylphosphonium bromide 

Downstream Products

• 157021-77-7 7-(tert-Butyl-dimethyl-silanyloxy)-1-(triphenyl-λ⁵-phosphanylidene)-heptan-2-one 

Relevant academic research and scientific papers

Biomimetic model studies towards ptilomycalin A

Six model compounds, the tetracycles 14 and 15, the tricyclc 20 and the pentacycles 26, 30 and 32 have been prepared to illustrate a biomimetic approach to the guanidine containing natural product ptilomycalin A 1.

Synthesis of a Pentacyclic Model of Ptilomycalin A

The conversion of dienes 3 and 10 into the pentacyclic guanidine compounds 6 and 11 is reported; their preparation illustrates a potentially biomimetic synthetic route to the biologically active natural product Ptilomycalin A 1.