82007-05-4 Usage
General Description
FMOC-LEU-GLY-OH is a chemical compound commonly used in peptide synthesis. It is composed of three amino acids - leucine, glycine, and an FMOC (9-fluorenylmethoxycarbonyl) protecting group. The FMOC group is commonly added to the N-terminal of peptides to protect the amine group from unwanted reactions during synthesis. Leucine is an essential amino acid used in protein synthesis and is important for muscle growth and repair. Glycine is the smallest amino acid and is known for its role in the production of collagen, a protein that supports skin, bone, and connective tissue. FMOC-LEU-GLY-OH is used in research and pharmaceutical industries for the development of new peptide-based drugs and biological studies.
Check Digit Verification of cas no
The CAS Registry Mumber 82007-05-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,0,0 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 82007-05:
(7*8)+(6*2)+(5*0)+(4*0)+(3*7)+(2*0)+(1*5)=94
94 % 10 = 4
So 82007-05-4 is a valid CAS Registry Number.
82007-05-4Relevant articles and documents
Solid-phase peptide synthesis and solid-phase fragment coupling mediated by isonitriles
Wang, Ting,Danishefsky, Samuel J.
, p. 11708 - 11713 (2013/08/23)
The synthesis of polypeptides on solid phase via mediation by isonitriles is described. The acyl donor is a thioacid, which presumably reacts with the isonitrile to generate a thio-formimidate carboxylate mixed anhydride intermediate. Applications of this
'Glycylcyclines'. 3. 9-Aminodoxycyclinecarboxamides
Barden,Buckwalter,Testa,Petersen,Lee
, p. 3205 - 3211 (2007/10/02)
A series of 9-(acylamino)doxycycline derivatives has been prepared. These analogs exhibit good activity against both tetracycline sensitive and tetracycline resistant Gram-positive (Staphylococcus aureus) and Gram- negative (Escherichia coli) bacteria tha