82020-90-4 Usage
Classification
Triazine antifolate
Enzyme target
Dihydrofolate reductase
Synthesis involvement
DNA, RNA, and proteins
Potential use
cancer treatment
Combination therapy
with other chemotherapy drugs
Promising results
in preclinical and clinical studies
Cancer types studied
lung, breast, ovarian
Mechanism of action
inhibition of dihydrofolate reductase
Ability to overcome resistance
to other antifolate drugs
Ongoing research
for cancer therapy.
Check Digit Verification of cas no
The CAS Registry Mumber 82020-90-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,2,0,2 and 0 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 82020-90:
(7*8)+(6*2)+(5*0)+(4*2)+(3*0)+(2*9)+(1*0)=94
94 % 10 = 4
So 82020-90-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H13N5O/c1-4(2)9-6-10-5(8)11-7(12-6)13-3/h4H,1-3H3,(H3,8,9,10,11,12)
82020-90-4Relevant articles and documents
Preparation of 2-amino-4-alkoxy-s-triazines
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, (2008/06/13)
2-Amino-4-alkoxy-s-triazines which are substituted by an alkyl, aryl or aralkyl moiety in the 6-position and which are useful as pharmaceutical agents and as intermediates for herbicides, dyes and optical brighteners are prepared by reacting a dialkyl (N-cyanoimido)carbonate with an amidine salt in the presence of an inert solvent and a base.
