820216-75-9

Upstream product

• 820216-78-2 methyl 3α-azido-7α-amino-12α-[N-(o-nitrobenzenesulfonyl)amino]-5β-cholan-24-oate 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 820216-81-7 4-{3-azido-7-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-12-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionylamino]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl}-pentanoic acid methyl ester 
• 820216-85-1 4-{3-amino-7-(2-tert-butoxycarbonylamino-3-methyl-butyrylamino)-12-[2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionylamino]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl}-pentanoic acid methyl ester 
• 820216-80-6 (R)-4-{(3R,5R,7R,8R,9S,10S,12S,13R,14S,17R)-3-Azido-7-tert-butoxycarbonylamino-12-[(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionylamino]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl}-pentanoic acid methyl ester 
• 820216-84-0 (R)-4-{(3R,5R,7R,8R,9S,10S,12S,13R,14S,17R)-7-Amino-3-azido-12-[(S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-phenyl-propionylamino]-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl}-pentanoic acid methyl ester 

Relevant academic research and scientific papers

Differentially-protected steroidal triamines; scaffolds with potential for medicinal, supramolecular, and combinatorial chemistry

Cholic acid 2a has been converted into two new orthogonally-protected triamino scaffolds, 13 and 14. The synthesis proceeds via the bis-Boc-NH-substituted azide 10, for which an improved preparation is described. After removal of the Boc groups, the two a