820222-63-7

Usage

Uses

Used in Organic Synthesis:
1(2H)-Pentalenone,hexahydro-3a,6a-dimethyl-,(3aR,6aR)-rel-(9CI) is used as a building block for the synthesis of more complex organic molecules due to its unique structure and potential reactivity.
Used in Chemical Research:
1(2H)-Pentalenone,hexahydro-3a,6a-dimethyl-,(3aR,6aR)-rel-(9CI) is utilized as a subject of study in chemical research to understand its properties, reactivity, and potential applications in various chemical processes.
Used in Pharmaceutical Development:
1(2H)-Pentalenone,hexahydro-3a,6a-dimethyl-,(3aR,6aR)-rel-(9CI) may be used as a starting material or intermediate in the development of new pharmaceuticals, taking advantage of its specific structural features and reactivity.

Upstream product

• 137740-19-3 (-)-(1R,5S)-1,5-dimethylbicyclo[3.3.0]octane-2,7-dione 
• 137740-18-2 (1S,5R)-6-isopropylidine-1,5-dimethylbicyclo[3.3.0]octan-3-one 
• 820222-48-8 6,6-dimethyl-spiro[3.4]octan-5-one 
• 581096-83-5 ethyl [(1S,3S)-3-isopropenyl-1-methyl-2-methylenecyclopentyl]acetate 
• 581096-85-7 1-Diazo-3-((1S,3S)-3-isopropenyl-1-methyl-2-methylene-cyclopentyl)-propan-2-one 
• 581096-86-8 (1R,3R,6S,9S)-9-isopropenyl-6-methyltricyclo[4.3.0.0(1,3)]nonan-4-one 
• 581096-84-6 [(1S,3S)-3-isopropenyl-1-methyl-2-methylenecyclopentyl]acetic acid 
• 581096-88-0 (1S,5S,6S)-6-isopropenyl-1,5-dimethylbicyclo[3.3.0]octan-3-one 
• 581096-91-5 (1R,5S)-1,5-dimethylbicyclo[3.3.0]octane-spiro[7,2']-1,3-dithiolan-2-one 

Relevant academic research and scientific papers

Enantiospecific first total synthesis of cucumin-H

Enantiospecific first total synthesis of the linear triquinane sesquiterpene cucumin-H has been described. (R)-Limonene has been employed as the chiral starting material and a combination of Claisen rearrangement, intramolecular cyclopropanation and Nazar

Synthesis and rearrangement of [1,1′-bicyclobutyl]-1-ols and spiro[3.4]octan-5-ols: A general access to bicyclo[3.3.0]octenes (hexahydropentalenes)

Several new Grignard reagents based on substituted cyclobutanes have been generated and added to cyclobutanones to yield mono- to trimethylated [1,1′-bicyclobutyl]-1-ols. Mono- to trimethylated spiro[3.4]octan-5-ols have been prepared from the parent ketone via alkylation and/or addition reactions. Upon treatment with acid, all [1,1′-bicyclobutyl]-1-ols and spiro[3.4]octan-5-ols rearrange to yield a single bicyclo[3.3.0]octene. Mono- to trimethylated [1,1′-bicyclobutyl]-1-ols and spiro[3.4]octan-5-ols have been synthesized and rearranged to yield a single bicyclo[3.3.0]octene in each case. Examples are 42, 43, 44 and 45.

Enantiospecific first total synthesis and assignment of absolute configuration of the sesquiterpene (-)-cucumin H

(Matrix presented) The first total synthesis of the sesquiterpene (-)-cucumin H, a linear triquinane isolated from Macrocystidia cucumis, has been accomplished starting from (R)-limonene employing two different cyclopentannulation methodologies, which in